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刘继田 副研究员


一、基本情况

刘继田,男,国精产品满18岁副研究员,药物化学专业硕士生导师,2020年入选山东大学青年学者未来计划。作为项目负责人主持山东省自然科学基金等项目两项。目前以第一作者或通讯作者身份在ACS catalysis,Green Chemistry,Organic Chemistry Frontiers等期刊发表SCI文章10余篇,以第一发明人获得中国发明专利授权5项。

通讯地址:山东省济南市历下区文化西路44号山东大学趵突泉校区

E-mail: liujt@sdu.edu.cn

二、研究领域

1.活性天然产物全合成及结构修饰

2.基于新型核酸药物递送系统的药物载体的开发与合成

3.药物分子中季碳手性中心的不对称构建方法学研究

三、学习和工作经历

2019.09至今, 国精产品满18岁,副研究员

2017.02-2019.08,北京大学,博士后

2015.09-2016.09,威斯康星大学麦迪逊分校,联合培养

2012.09-2017.01,天津大学,博士

2009.09-2012.06,中国海洋大学,硕士

2005.09-2009.06,中国海洋大学,本科

四、教学工作

本科生课程《有机化学》、《人名反应在药物合成中的应用》、《化学与人类文明》

五、承担课题

1.山东省自然科学基金青年项目(ZR2020QB017),2021.01-2023.12,主持

2.山东大学青年学者未来计划,2021.01-2025.12,主持

六、代表性文章

1. Gao, Can; Zhang, Ting; Li, Xiaoxun; Wu, Jingde*;Liu, Jitian*;Asymmetric Decarboxylative [3+2] Cycloaddition for theDiastereo- and Enantioselective Synthesisof Spiro[2.4]heptanesvia Cyclopropanation.Organic Chemistry Frontiers,2022,DOI: 10.1039/D2QO00124A.

2. Xunhua Wang#; Can Gao#;Jitian Liu*; Xiaoxun Li*; Highly Diastereo- and Enantioselective Synthesis of Tetrahydrobenzo[b]azocines via Palladium-Catalyzed [4 + 4] Cycloaddition,ACS Catalysis,2021,11, 2684-2690.

3. Xinhui Yu#, Ting Zhang#,Jitian Liu*, Xiaoxun Li*; Recent Advances in the Construction of Quaternary Stereocenters via Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation,Synthesis,2021,53, 4341-4352.

4.Liu Jitian*; Ye Wen-jing; Wang Shuo-jin; Zheng Jun-rong; Tang Wei-ping; Li Xiao-xun*; Synthesis of Lactams via Ir-Catalyzed C–H Amidation Involving Ir-Nitrene Intermediates,Journal of Organic Chemistry,2020,85, 4430-4440.

5.Liu, Jitian; Yang, Shiyi; Tang, Weiping; Yang, Zhanhui*; Xu, Jiaxi*; Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading,Green Chemistry,2018,20, 2118-2124.

6.Liu, Jitian; Simmons, Christopher J.; Xie, Haibo; Yang, Fan; Zhao, Xian-liang*; Tang, Yu*; Tang, Weiping*; Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation,Advanced Synthesis & Catalysis,2017,359, 693-697.

7.Liu, Jitian; Do, Truman J.; Simmons, Christopher J.; Lynch, John C.; Gu, Wen; Ma, Zhi-Xiong; Xu, Wei; Tang, Weiping*; Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors,Organic & Biomolecular Chemistry,2016,14, 8927-8930

8.Liu, Jitian; Tang, Yu*; Fu Xu; Efficient conversion of carbohydratesto ethoxy-methylfurfural and levulinic acid ethyl ester under the catalysis of recyclable DMSO/Br➢nsted acids.Starch/Stärke,2015,67, 765-771.

9. Tang, Yu*;Liu, Jitian; Chen, Ping; Lv, Ming-can; Wang, Zhen-zhen; Huang, Yi-kun; Protecting-Group-Free Total Synthesis of Aplykurodinone-1,Journal of Organic Chemistry,2014,79, 11729-11734

10.Liu, Jitian; Tang, Yu; Wu, Kaigui; Bi, Caifeng; Cui, Qiu; Conversion of fructose into 5-hydroxymethylfurfural (HMF) and its derivatives promoted by inorganic salt in alcohol.Carbohydrate Research,2012,350, 20-24.

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